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EpiFix Poster Received Highest Score at Symposium on Advanced Wound Care

The MiMedx Group, Inc. (NASDAQ: MDXG) poster detailing the EpiFix® case study received the award for the highest scoring abstract in the case study category at the recent Symposium on Advanced Wound Care ("SAWC").

The abstract titled A Long-term Follow-up Study of Chronic Diabetic Foot Ulcers Healed with Dehydrated Human Amniotic/Chorionic Membrane Allografts was recognized at the SAWC as the highest scoring poster abstract in the Case Study category.

Six poster abstracts presented results of treatment with EpiFix® for a wide range of applications, including the treatment of non-healing wounds, pressure ulcers in spinal cord injured veterans, diabetic foot ulcers and intractable ulceration. The poster abstracts presented case and study results that showed closure of multiple different types of non-healing wounds using EpiFix®. In one poster abstract comparing EpiFix® with a competitor's human fibroblast derived dermal substitute, the study cases demonstrated an 82% reduction in cost of wound closure in non-healing wounds treated with EpiFix®. In another poster abstract, the case study examined the use of EpiFix® for the treatment of difficult intractable wounds and concluded that difficult wounds which did not heal after treatment with a payer approved amount of bioengineered skin substitute, even those wounds secondary to radiation, responded and healed with EpiFix® treatment.

Mr. Pete Petit, Chairman and CEO of MiMedx, said "In general, the abstracts accepted for presentation at the SAWC cited the use of EpiFix® for treatment of wounds that previously were treated with commercially available living cell skin substitutes without wound closure and healing, but had successful healing and closure with EpiFix®."

Each year, the SAWC recognizes the highest scoring poster abstracts in four categories: Case Study, Clinical Research, Informational/Educational Report, and Laboratory Research. The winning poster presented a case series following up on the rates of recurrence of chronic DFUs after previous healing with use of EpiFix®. Evaluation of clinical records was made with IRB approval and patient consent. Eighteen of 22 eligible patients returned for follow-up examination, which was conducted 9 – 12 months after original healing with EpiFix®. Only one patient had recurrent DFU during the follow-up period, while 17, or 94.4%, remained fully healed. These findings support the long-term effectiveness of dehydrated human amnion/chorion membrane ("dHACM") for treatment of DFU. The study concluded that dHACM is a clinically viable and economically feasible treatment option that should be considered by clinicians who treat diabetic pedal ulcers.

Mr. Petit added, "We are pleased that an abstract identifying the impressive healing properties of our EpiFix® allograft received this top recognition. The identification and implementation of an ideal treatment regimen for diabetic foot ulcers is an increasingly common issue faced by clinicians. Therapies that promote rapid and complete healing, thus reducing the risk for infection and amputation, can substantially improve quality of life while decreasing financial burdens. We believe our EpiFix® allograft is a clinically effective and economic solution to these needs."

Bill Taylor, President and COO of MiMedx, stated, "Human amniotic membrane has been used as an allograft to treat wounds for over a century. However, our proprietary PURION® process has led to the development of our EpiFix® dHACM allograft. Studies have shown strong clinical and cost effectiveness of EpiFix® for healing of diabetic foot ulcers, pressure ulcers, and wounds that have failed to heal with other treatment modalities with minimal, if any, waste. Use of competitive skin substitutes routinely result in waste of over 75% of their graft because they come in only one very large size, which is generally at least 15 times greater than the average diabetic foot ulcers. EpiFix® has size appropriate grafts and does not waste such material."